Crystal Structure of a Complex Between Human Spliceosomal Cyclophilin H and a U4/U6 snRNP-60K Peptide
نویسندگان
چکیده
منابع مشابه
Crystal structure of a complex between human spliceosomal cyclophilin H and a U4/U6 snRNP-60K peptide.
The spliceosomal cyclophilin H is a specific component of the human U4/U6 small nuclear ribonucleoprotein particle, interacting with homologous sequences in the proteins U4/U6-60K and hPrp18 during pre-mRNA splicing. We determined the crystal structure of the complex comprising cyclophilin H and the cognate domain of U4/U6-60K. The 31 amino acid fragment of U4/U6-60K is bound to a region remote...
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ژورنال
عنوان ژورنال: Journal of Molecular Biology
سال: 2003
ISSN: 0022-2836
DOI: 10.1016/s0022-2836(03)00684-3